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CBD and the Future of Sports Medicine

Why CBD is becoming the go-to for Athletes

Athletes are remarkable creatures. From a young age they show innate physical ability and continue to hone their skills through years of fierce dedication and hard work. Some go on to become world-class champions, record breakers and gold medalists and experience the kind of glory most of us can only dream of. But with glory comes injury and chronic pain. Pushing through punishing conditions takes its toll and for athletes, it’s what is expected.

And so it is, athletes get hurt A LOT —and turn around and go right back to competing. Eventually walking it off is no longer an option and they must deal with their ailments – everything from torn ligaments to broken bones and everything in between. They turn to doctors and coaches, most of whom inevitably point them down the path to pain medicine.

If taken too long, this practice can turn into over-reliance or over-indulgence; even addiction. It’s clear that professional and collegiate athletes are not immune to these dangers; if anything, they are more susceptible because they get hurt more often.

A Vicious Cycle

An over-reliance on painkillers and prescription drugs is nothing new. In the high-stakes game of professional sports, getting injured has far reaching consequences. Time away from the game can mean losing a position at the top, sponsorship or money– things that loom heavy on the minds of pro athletes everywhere.

It is no surprise that opioids and anti-inflammatories like NSAIDs are the first line of defense for athletes dealing with injury. While prescription medications have their place, there are a host of issues when used too frequently, namely a myriad of side effects and negative interactions with other substances.

Even anti-inflammatories at higher doses/frequency can be dangerous. In fact, the National Vital Statistics reported NSAID deaths as the 15th leading cause of death in the US. The longer-term health effects from anti-inflammatories (like naproxen) and opioids (like fentanyl) are equally grim and include cardiac health issues, kidney failure, and worsening respiratory conditions.

A New Option

Thankfully, many professional athletes and a few of the professional sports leagues around the world have started embracing alternative methods of pain relief like CBD.

CBD, the main non-psychoactive ingredient in cannabis, offers many impressive advantages over standard pain medicine such as no side effects, unusual interactions or risk of addiction – just to name a few.

CBD and other cannabinoids also work in tandem with the body’s own endocannabinoid system to achieve homeostasis, which further increases the body’s ability to recover and heal itself. Here are just a few of the many benefits athletes can expect from using CBD:

Help with inflammation – Inflammation is the most common type of pain athletes experience. CBD has long been associated with both anti-inflammatory and immunosuppressive qualities. Several studies show that cannabinoids downregulate cytokine and chemokine production and, in some models, upregulate T-regulatory cells (tregs) as a mechanism to suppress inflammatory responses.

Combat oxidative damage – CBD is a powerful antioxidant-, more powerful than Vitamins C and E. Cannabinoids have long been known to act as free radicals that help protect the brain and body and reverse oxidative injury.

Pain relief and muscle recovery – Pain relief is the number one reason athletes turn to CBD. It’s safer,less addictive and the neuroprotective and antispasmodic qualities help reduce muscle spasms. It also acts as an analgesic, which helps alleviate pain pre and post workout.

Chronic use of pain medication, even over-the-counter pain relievers, can create a host of problems. Not only is this country grappling with an opiate epidemic, but medical science is now uncovering many health risks associated with anti-inflammatories that were previously not known. Professional athletes are right to be concerned as they are one of the groups most susceptible to these dangers. It comes as no surprise that they have started actively seeking alternatives to pain relief and overall wellness, with CBD on the top of their list. (And with good reason!)

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A Guide to Cannabinoids – The Science, The Synergy and its Role in Society

People today are more eager than ever to take a more active role in their overall health and wellness. The recent spike in popularity for cannabis and cannabinoid-rich products is a reflection of this movement- one that has led many to want to cultivate a more intentional relationship with this healing herb.

In the last several years there’s been a big spotlight placed on cannabis. It seems as though this medicinal plant is finally getting the recognition it deserves for the many health benefits it offers.  As cannabinoids become one of the most sought-after natural products on the market, we see consumers eager to ask more questions on a personal quest to learn as much as they can about the topic. For this reason, a helpful guide to cannabinoids can assist in educating and clarifying some of the finer points relating to the science of, and the synergy between cannabinoids, as well as some broader questions pertaining to its current place in modern society.

Let’s get started…

The Science-

Cannabinoids affect many important functions in the endocannabinoid system in our bodies. CBD for instance has pain relieving, antioxidant, anti-inflammatory and anti-nausea effects, while CBN has been shown to act as a sedative, and is helpful in managing anxiety, while CBC has antibiotic, antifungal, anti-inflammatory properties and helps relieve pain and so on. There has been extensive research regarding the internal interplay when cannabinoids, flavonoids, terpenes and fatty acids all work in concert to abate symptoms of pain, inflammation, depression, anxiety, fungal, bacterial infections and more.

Each cannabinoid has a different and beneficial effect in our body. Here are some of the more common ones along with their specific function:

  • Cannabinol (CBN): sedative, antibiotic, anticonvulsant, and anti-inflammatory.
  • Cannabidiol (CBD): anticonvulsant, antioxidant, reduces anxiety, treats psychotic disorders, relieves pain, reduces inflammation, and relieves spasms
  • Tetrahydrocannabinol (THC) ; antioxidant, anti-inflammatory, induces a euphoric high, relieves pain
  • Cannabigerol (CBG): antibiotic, anti-fungal, anti-inflammatory, and relieves pain
  • Cannabichromene (CBC): antibiotic, anti-fungal, anti-inflammatory, and relieves pain.
  • Tetrahydrocannabivarin (THCV): induces a euphoric high and relieves anxiety.

 

But how does it work?…

Cannabinoids have a profound and positive impact on the body’s own receptor system. Scientists are still trying to figure out exactly how those chemical compounds interact with each other and within the human body. Although there is increasing evidence that there may be more types, today we know about two receptors: CB1 and CB2. These receptors are distributed on the surface of many different types of cells in the body. CB1 receptors are found primarily on neurons in the brain- like in the amygdala, which influence emotions such as fear and anxiety. A high density of CB1 receptors are also found in the hippocampus, those influence the learning and absorption of new information as well as memory integration. As for the second class of receptor, CB2, those are more abundant in the central nervous system and in the peripheral tissues and organs, particularly in the immune system cells and thus are thought to act in a primarily protective role.

-The Synergy-

Medicinal plants like cannabis contain a wide variety of potentially beneficial compounds. Choosing between full-spectrum and isolate-type products is an important choice when deciding what products to start using. In full-spectrum phytocannabinoid products, the “whole-plant” is used and nothing is held back or left out. That is because whole-plant or FULL-SPECTRUM products are known to include not just CBD but trace amounts of different cannabinoids which introduce various potential benefits that can address a wide variety of ailments both on their own and in conjunction with one another. An isolate is of course effective but studies show that full spectrum CBD is capable of offering greater levels of relief. That is because full-spectrum oils include a wide range of cannabinoids which work synergistically. People seem to respond better to products which contain multiple cannabinoids opposed to single cannabinoids in isolation. And, unsurprisingly, this finding is in line with how cannabinoids are found in nature as opposed to being produced synthetically in a lab. As we can see, when certain isolated components are combined together, they produce a greater more tangible benefit to the user—and this interaction actually has a name, it’s known as the entourage effect.

The term entourage effect was first used decades ago by two Israeli scientists Shimon Ben-Shabat and Raphael Mechoulam upon realizing that cannabinoids found in the cannabis plant actually work in a similar way as the body’s own endocannabinoid system. Each separate cannabinoid has a different and beneficial effect in our body. While researchers agree that more studies are needed to understand the entourage effect, many can attest that the heightened efficacy when compounds operate together is real and not imagined.  Not only can this be seen between certain cannabinoids but also in how terpenes and flavonoids work synergistically increasing the cerebral blood flow while impacting the blood-brain barrier.  As research continues, our knowledge will collectively broaden. The good news is that the field is wide open for greater exploration and development.

Society-

As the popularity of hemp-derived products continue to grow, so has its acceptance across many of the states in America. Just this summer, a major step was taken to pass legislation that would legalize hemp as part of the 2018 Farm Bill. Many agree we seem to be moving in the right direction amidst the changing political landscape of today although, “Is it legal?” is still a common question. Many wish the answers were more straightforward but the reason for the current murkiness is because there are different laws in different states, as well as different laws at the state and also federal levels.

CBD oil that is hemp-derived and consists of no illegal amounts of THC is legal in most states. As of this year, there are states where the recreational and medicinal use of cannabis is also completely legal. They are Colorado, Maine, Massachusetts, Nevada, Oregon, Washington and Alaska. That means if you live in these states, you are free to use CBD and other products without a prescription. Unfortunately, it seems as though laws are constantly in flux, which adds to the legal confusion. Hopefully, there will be more clarity and consistency coming from state and federal authorities sometime in the near future.

So the short answer to, “Is it legal?’ is, there is no short answer. You must check the local law in the state where you live- and stay up on any and all changes. If you live in a state where the recreational use of cannabis is legal, you can use CBD that comes from marijuana or hemp without issue (with the exception of California and provided you are at least 21 years of age). If you live in a state where medical cannabis is legal, and you have a prescription, you are also in the clear. For everyone else in the country, the laws surrounding CBD are stuck in a temporary gray zone. Eventually, many believe that all the states in the country, even the most culturally conservative ones will submit to peoples’ demands and the growing scientific research and legalize cannabis use for medical purposes- once and for all.

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Cannabinoids Cannabis Events Cannabis Oils Cannabis Plant Feature Story Hemp Oil In the News Uncategorized

Cannabinoids, CBD and One Woman’s Journey with Multiple Sclerosis – A Personal Story

Ingrid was barely 26 years old when she was first diagnosed with multiple sclerosis (MS). The first sign something was amiss came when she was on vacation in the Dominican Republic in the early 1980’s. She woke up in her hotel room with double vision- in both eyes. She walked over to the mirror but all she could see was a hazy gray cloud staring back at her. She went to a nearby clinic in Santo Domingo but they didn’t really know what to tell her. After a general exam, they asked if she had insurance back home and recommended she see a doctor as soon as she got back. She had just had her first baby and decided not to tell my parents about the incident. When she landed in Miami, with her vision back intact, she dismissed the experience as a one-off and went back to work on Monday. Six months later she was driving home from work during the tail end of rush hour. She remembers the night was warm and the flickering brake lights reminded her of the dusky, setting sun. As the traffic around her came to a stop, she placed her foot on the brake, or tried to, but her leg did not respond. She tried again. Nothing. She recalls how terrifying it was realizing she could not move her leg, it was as though her brain and body were not connecting. And she was right. She slammed into the cars in front of her but luckily no one was seriously hurt. After that incident she went to a doctor, got a spinal tap and was diagnosed with multiple sclerosis.

And that is how, on a warm summer night, her journey with MS began- as well as our family’s journey with MS. For the next two decades my sister would be in remission. She worked a full time job (took the train to work) and managed to have three more children. She just became a grandmother in her 50’s, and has a large, loving and supportive family around her. But this progressive disease finally caught up to her. She is now unable to stand on her own or bathe herself independently and spends most days in a wheelchair in front of the television.

Cannabis has been used for medicinal purposes throughout centuries and is now recommended and prescribed to manage the symptoms of multiple sclerosis and other neurodegenerative diseases. I have been researching the beneficial effects of cannabis in multiple sclerosis for years but there is still much to be done in the way of education and clinical testing. Even so, anecdotal as well as many randomized placebo-controlled clinical trials have shown the efficacy of various cannabinoid treatments in managing spasticity, pain, bladder problems, sleep disturbances and tremor due to MS.

Every case of MS is different as is every person affected. Thankfully my sister does not suffer from pain-related symptoms. She’s had two seizures though, back to back in recent years and because of them has suffered some cognitive loss as well as other progressive symptoms like tremor and incontinence. She was able to obtain a license for medical marijuana this year and was prescribed a medicine which contained some THC, the main psychoactive component of cannabis.

She accepted the recommendation of the clinician without question or doubt. However, in no time we noticed some disturbing side effects. Things like short-term memory impairment, some disruption in her psycho-motor control and a somewhat weird, and distorted sense of time. For example, in July she asked where the Christmas decorations were. Around the same time, her caretaker reported panic on my sister’s part during a routine hair-washing session. This was unlike her and was clearly not the intended result and definitely not what we expected. I felt guilt having been the one to propose the idea that she start this regiment in the first place. What did I miss? It was a big anti-climactic disappointment; we had waited months for the license and had high hopes that it would bring her some relief. But the opposite occurred- this prescribed cannabis treatment not only didn’t work, it actually made her worse.

I knew that cannabinoids mimic naturally occurring compounds in the body called endocannabinoids. Endocannabinoids have been widely studied and implicated in a variety of physiological functions specifically with MS. When we take in cannabinoids, they interact with the same receptors found in all human cells. What I didn’t fully appreciate was that THC (tetrahydrocannabinol) affects the central nervous system (CNS) through these receptors- most densely in the frontal cortex and hippocampus. Cognition, especially in certain groups, such as patients suffering from diseases of the CNS like my sister, were particularly vulnerable to adverse effects.  However, some of the other constituents of cannabis, such as CBD (cannabidiol), have well-documented biological effects like anti-anxiety and anticonvulsive properties without any of the psychotropic actions. We realized that CBD might hold greater therapeutic potential for her than THC or any combination containing THC, since the psychoactive properties that accompany THC did not agree with her at all.  

We decided to give it one more shot and take matters into our own hands. We were on the lookout for a high quality- hemp derived, Full Spectrum CBD product. We were fortunate to find RAW, a high-grade, cannabinoid oil tincture. It contains unfiltered industrial full spectrum hemp oil, coconut MCT oil, and vitamin E as well as a variety of valuable phyto-nutrients, synergistic cannabinoids and essential oils. With RAW, we hit the jackpot. Not only did it work well, but it began working almost immediately.

One of my focuses of my freelance writing in the cannabis and medicinal marijuana space was to help my sister combat her MS symptoms and to help her live a fuller life. I saw that start to happen with RAW. As someone who does consistent research on the subject, I recommend this product as well as encourage everyone to do their own research.

From my experience, and from interviewing others, I understand that the manufacturing and selling of CBD products has become big business. I now know how to discern the differences between high quality products and subpar products as well as understand the different extraction methods available. Other finer points like the question of full spectrum vs. isolate products are important to understand before making a decision.

Ingrid began using RAW in the morning and at night, taking .5ml under her tongue, twice a day. After about a week she experienced less spasticity, less fatigue and tremor, and was just more alert and lucid. We have also seen a big improvement with her MS-related urinary symptoms. Her increased sense of well-being is also visible; the other day she commented that she “felt really strong”. When she visits her daughters, we pack ETS’s new veggie capsules in her overnight bag- we find that it’s easier for her to manage when she’s traveling.

We were concerned initially how this new regiment would interact chemically with her other prescribed drugs- but so far, she’s had no issues. We are thrilled, over the moon, and grateful that we didn’t give up. And you shouldn’t either. Cannabis derived compounds can hold real potential for those looking to treat symptoms of MS. The most important points to keep in mind are quality and consistency. You need to do your research, seek out the highest quality product you can find, and stay consistent with the dosing. For those looking to try any of EST’s products, the great news is you do not need a special marijuana card or prescription to do so.

Click here find out more about ETS.

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Terpenes And Flavonoids part of the Synergy

There’s been a lot of talk lately about the positive effects of the hemp plant on everything from insomnia to pain relief to inflammation- and the list keeps growing. People everywhere are curious to learn as much as they can about the healing properties of this plant, and in turn, eager to go back and share what they know. As new research emerges about this plant, its individual components, and how they interact with each other, so too does our own understanding and knowledge on how best to treat, medicate and heal ourselves with it.

Two cannabinoids in particular – THC and CBD – get the most air time but within this complex plant exists other chemicals and compounds that are beneficial and play a unique and integral role.

Bottom line: they all interact synergistically to heal the body and mind.

Let’s start with terpenes (pronounced tur-peens)

What are terpenes?

Imagine for a moment the whiff of freshness that meets the nose when one peels an orange or the sweet, floral scent that announces itself in a tub filled with lavender. What you are smelling are terpenes, a bouquet of oils secreted in the same glands that produce cannabinoids. They lend their impressive aromaticity, taste and color to a countless number of plant species—but that’s just part of their charm.

The development of terpenes, from an evolutionary perspective, began for adaptive reasons—to repel insects and other predators and to lure pollinators. The plant’s medicinal properties can be traced to this enduring evolutionary feature- the pungency that prevented fungus long ago is still fighting bacteria and respiratory pathogens in people today.  

Like cannabinoids, terpenes bind to receptors in the brain and give rise to various medicinal properties. When cannabinoids and terpenes interact synergistically, they create what scientists refer to as an “entourage effect”  

The most commonly studied terponoids are limonene, myrcene and alpha-pinene but there are over 200 that have been identified in cannabis. For instance, the combination of CBD with terpenes-driven compounds like mint and capsaicin provide targeted relief from joint and muscle pain and soreness. They also work well on tension headaches and migraines.  

Terpenes have also been shown to act on neurotransmitters – dissolving in lipids or fats and relieving anxiety as serotonin uptake inhibitors (if that term sounds familiar it’s because you’ve heard it in commercials about antidepressants like Prozac). They also enhance norepinephrine and dopamine activity in the brain.

While many of the flavors and aromas of cannabis can be attributed to terpenes flavonoids also play an important role.

Let’s move on to flavonoids: (pronounced flavo-noids)

What are flavonoids?

Flavonoids account for roughly 10% of the compounds produced by cannabis and are known for their antioxidant and anti-inflammatory health benefits. Many plants including fruits and vegetables owe their bright colors in part to flavonoids.  The 20 or so varieties known to exist in cannabis are called cannaflavins and they don’t just help contribute to the vibrant color we see on the many foods we eat, they also smell good and are pharmacologically active (beneficial). Similar to CBD, flavonoids interact on many different sites in the body through complex biochemical mechanisms, some interacting with estrogen receptors others as potent antioxidants. For instance, the flavonoid quercetin, found in many fruits and vegetables is known for its anti-fungal and antioxidant properties. Catechins, a highly active flavonoid found in cannabis (as well as cocoa, teas and pome fruits) is also known to be an effective antioxidant with cardiovascular health benefits. Cannaflavin A has been found to reduce inflammation by inhibiting the inflammatory molecules PGE-2 and it does this 30 times more effectively than aspirin.

Flavonoids are yet another member of the ‘entourage’, binding to CB receptors and interacting synergistically with cannabinoids. In fact, CB receptors bind to all of the cannabinoids, terpenes and flavonoids that are ingested. These compounds trigger a chemical cascade throughout the body. They also bind to opioid receptors- the same sites that activate after binding with painkillers like Vicodin, Percocet or morphine. Flavonoids provide painkilling properties that aren’t available from just terpenes and cannabinoids alone and best of all, they are non-addictive.

The general understanding of this miracle plant can sometimes be overly simplistic. THC and CBD seem to get the most mention but in reality, hundreds of chemical components are working in tandem; the two biggest groups being flavonoids and terpenes. The entourage effect suggests that any one chemical or compound, taken on its own, will have a far less reaching effect than the combined efforts of all its parts. So, while THC and CBD may seem like the show stoppers, especially where this plant is concerned, the whole is definitely greater than the sum of its parts. Terpenes and flavonoids are two perfect examples.

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Industrial Hemp: Senate’s 2018 Farm Bill Makes Way for Economic Growth

After 77 years of heavy restrictions by the federal government, industrial hemp is inching closer to becoming just like any other commodity crop. It’s been a long road and the battle is still not over but on June 28th the Senate took a major step forward and passed legislation legalizing hemp as part of the 2018 Farm Bill.

The bill includes all the language from Mitch McConnell’s, (R-KY), Hemp Farming Act, which was just introduced in April of this year with the help of Senators Ron Wyden, Rand Paul and Jeff Merkley. The House farm bill also passed on June 21st so now with the passing of the Senate’s version, the permanent legalization of hemp is one step closer to becoming reality.

There are still some steps left in the process but Leader McConnell and the array of bi-partisan supporters should secure that it is signed into law soon. That would mean that hemp would finally be permanently removed from the purview of the Controlled Substances Act. The Farm Bill would also give states the chance to become primary regulators of hemp production as well as allow hemp researchers to apply for competitive federal grants from the U.S Department of Agriculture. In addition, hemp farmers would also be eligible for crop insurance. Following a bi-partisan 86-11 vote, McConnell praised the passage of the bill and added, “Consumers across America buy hundreds of millions in retail products every year that contain hemp, but due to outdated federal regulations that do not sufficiently distinguish this industrial crop from its illicit cousin, American farmers have been mostly unable to meet that demand themselves. It’s left consumers with little choice but to buy imported hemp products from foreign-produced hemp.”

Of course there is never going to be a federal bill that pleases everyone. During the committee markup, Senator Charles Grassley (R-IA), one of Congress’s most staunch opponents of this law reform, threatened to challenge the current bill’s hemp provisions on the floor. Namely he wanted to remove the legalization of derivatives of the cannabis plant, such as cannabidiol (CBD), which is used by many people for medicinal purposes. But Grassley never ended up filing a floor amendment avoiding what would have been a contentious debate by hemp supporters. Overall the bill represents a solid effort by lawmakers as well as a timely one- bills are updated about every 5 years and the current one, the Agricultural Act of 2014, will soon expire.

The fundamentals of this Farm Bill rests squarely on the new, proposed definition of “hemp”, which explicitly adds cannabinoids and other derivatives to the definition and requires that hemp contain no more than 0.3% THC.

With the passing of this bill, the Senate seems serious about ensuring the future of American agriculture as well as strengthening the safety measures that directly help commodity producers. Here are some of the many benefits the new Farm Bill would have on the hemp industry:

  • Allow hemp production in all states- even those that have not yet acted to allow it
  • Remove newly defined hemp from the controlled substances list
  • Authorize CBD extraction from hemp flowers
  • Include U.S. grown hemp in the USDA National Organic Program
  • Open the door to research opportunities
  • Allow access to public water rights for hemp farmers
  • Fund safety net programs for farmers
  • Allow access to federal programs like crop insurance and low interest loans
  • Permit hemp production on tribal land and in Puerto Rico
  • Remove restrictions on intellectual property protection
  • Lower the adjusted gross income threshold at which farmers are no longer eligible for farm subsidies from $900,00 to $700,000

 

While there is no definitive timeline- the bill still needs to be merged with a competing version from the House before a final version can be sent to the White House for President Trump’s signature- hemp has broad bipartisan support and legalization is clearly on the horizon. The legalizing of hemp nationwide will finally end decades of bad policymaking and open up economic opportunities for many farmers across the country. There are high hopes for this bi-partisan legislation; many believe it could play a key role in the economic future of this nation by reversing damaging environmental trends, creating more jobs and bringing vitality back to rural farming communities. And that’s a good thing- especially for an industry that’s been in a major slump for 30 years.

 

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CDB Isolate vs. Full Spectrum

Whether it’s in the form of oil capsules, tinctures or edibles, CBD products are finally getting the recognition they deserve for the many health benefits they offer. And while it’s become a popular option for people seeking a natural alternative to a variety of ailments, parsing through the data can get challenging. If you’ve done any type of research at all  you’ve probably come across terms like CBD isolate and Full Spectrum –and perhaps are unsure what it all means or more importantly how it relates to your individual buying options and decisions. The good news is that these concepts are fairly simple to grasp and once you do, you’ll be better equipped to make an informed decision on which products to buy.

To start with, what do terms like “Isolate”, “Full Spectrum”, “Pure CBD” or “Whole Plant” mean? Good question!

CBD Isolate:

As the name suggests, a CBD isolate (also labeled “Pure CBD” or “CBD oil”) is a purified extract that has been separated from other cannabinoids, acids and chemicals found in the hemp plant.  In this pure and isolated form it is extremely well tolerated and effective in helping with pain, inflammation, mood and general health.

There are several extraction methods but generally the CBD is extracted using some type of solvent (this can be a liquid solvent, CO2, or an oil solvent), then filtered, heated and then isolated and processed into a powder. Isolate products such as these are usually 99% CBD and deliver the most amount of CBD to your system at once.

Initially it was thought that CBD isolates were more potent and effective on the whole but recent discoveries have shown that this may not be the case.  While CBD isolate packs a potent punch and remains the preferred treatment for many patients, many now believe that the pairing of the cannabinoids and terpenes (Full Spectrum) offers the most benefits of all.  

 

Full Spectrum:

Unlike the CBD isolate that’s been stripped of everything, a full-spectrum product contains all the therapeutic compounds cannabis has to offer; this include terpenes and other cannabinoids such as CBG, CBN and even some THC. Usually these will be in naturally occurring ratios and extracted from the plant and specific strain. This is where a multitude of flavonoids and polyphenols, which are vital micro nutrients, work together in synergy—the advantage of something called the entourage effect. For a large majority of average users, this high quality spectrum CBD oil will be the better and more efficient option.

In a 2015 study done at the Lautenberg Center for General Tumor Immunology in Jerusalem, research showed that in mice, CBD was much more effective when used along other compounds of the cannabis plant. Although they haven’t figured out exactly why, a full-spectrum CBD oil proved more effective at treating a majority of medical conditions than its isolated counterpart. The study concluded that CBD isolate becomes less effective over time, while the Full Spectrum continues its effectiveness. It was also concluded that a CBD isolate is only as effective as its dose, while the Full Spectrum extract continues its effectiveness as the dosage increases.

So why isolate molecules from this incredible plant in the first place? Great question. The answer is that CBD isolate is not only very effective on its own but also offers some convenient benefits. For instance, CBD isolate is easily measured so it lends itself well to mixing with oils or baking into edibles. Since it offers a high degree of control and is usually tasteless, it’s the preferred choice for flavored products.  Another advantage to products labeled as isolate is the fact that since nothing but CBD is in them, those who may be drug tested need not worry. When looking at an isolate product, one thing to keep in mind is the purity standard. While many products are in the 99.9% range with no identifiable amounts of THC, there are lower purity ones that may still have trace amounts that can show up in lab tests. This small amount is typically negligible and is nowhere near the amounts found in Full Spectrum products, but it is still something to be aware of for those seeking the purest form.

While some people find they respond better to an isolate—others appreciate the benefits of full-spectrum products– with over 100+ Cannabinoids and 100+ Terpenes, the possible combinations and blends are potentially endless! Still others prefer to use both the full plant extracts and isolates concurrently. Figuring out the best option for you will take a little time so be patient. Since everyone is different, trying out both will give you an idea of how each feels for you as an individual.