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Your Guide to Your Endocannabinoid System

Your endocannabinoid system is a crucial part of your body’s ability to function normally

We all know that cannabis products can have physiological impacts on our bodies. But do you know why? It’s because of your endocannabinoid system (ECS). When you ingest cannabis products, chemicals react with your ECS accordingly and can have a wide range of effects. Here’s what you need to know about what this system is and how it works.

What is the endocannabinoid system?

Your ECS on its own really has nothing to do with cannabis. Its name came about when scientists discovered it while researching marijuana.

The ECS is a biochemical communication system within your body. It regulates important aspects of our daily well-being, like our mood.

The CB1 receptors are located in the central nervous system, and the CB2 receptors are in the peripheral nervous system, digestive system, and immune system.

Cannabinoids, which are compounds found in cannabis, change the way your body’s physiological systems work. They trigger receptors, moderating the way we experience things.

Two cannabinoids from the plant that you’ve probably heard of are tetrahydrocannabinol (THC), and cannabidiol (CBD).

But there are actually over a hundred cannabinoids in hemp including cannabichromene (CBC), cannabidivarin (CBDV), cannabinol (CBN), and cannabigerol (CBG). There are endogenous (internally created) cannabinoids, or endocannabinoids, within our bodies, in addition to those that the plant cannabis produces.

How the ECS works

This ECS is made up of endocannabinoids, nervous system receptors, and enzymes. The endocannabinoids throughout your body bond with the receptors in the nervous system and enzymes then help to break them down.

What does that mean, exactly?

It’s important to understand the body’s process of homeostasis to explain how the ECS operates and affects you.

Homeostasis keeps everything stable and functioning within your body. This process monitors your environment and ensures that all of your levels are where they should be; things like temperature, hormone levels, and heart rate.

When your body is not functioning properly, your ECS kicks in. This system corrects your levels to help stabilize you.

There are two types of cannabinoid receptors in our bodies: CB1 and CB2. The CB1 receptors are located in the central nervous system is your brain and spinal cord, and the peripheral is the nerve network throughout your body that is connected to the brain and spinal cord.

These receptors regulate many important bodily functions, including our appetite, mood, sleep, memory, pain, and pleasure.

As you can see, the ECS is a necessary and natural part of your body. And, it’s the reason that you experience certain side effects when you introduce THC and CBD into your body.

What role does the ECS play?

If you ingest cannabis products in some form, you are taking cannabinoids into your body that have varying degrees of physiological effects.

For example, if you smoke marijuana, THC enters the ECS and attaches to receptors. This can actually interfere with the way your body naturally creates a balance between communicating neurons. This process creates those reactions to ingesting THC, such as slowing reaction time, impacting memory, increasing anxiety, or altering judgment.

Because these products stimulate the ECS, researchers continue to look into relief options and medications that include CBD. Some also say that a combination of THC and CBD is the way to go for pharmaceutical development.

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CBD and Post Traumatic Stress: How it Works

High-grade CBD-rich hemp oil may help relieve symptoms of PTSD

Post-traumatic stress disorder (PTSD) is a mental health condition that affects over 3 million people each year in the United States. The condition may last months, years, or even a lifetime.

It is a difficult condition to live with, and many people are distressed by the symptoms. If you or someone you love is struggling with PTSD, it can put a strain on your overall health and relationships. Fortunately, there are ways to alleviate some of the symptoms of PTSD with hemp products.

About PTSD

PTSD is a chronic condition that occurs after a person experiences a traumatic event.

Post-traumatic stress disorder (PTSD) is a mental health condition that affects over 3 million people each year in the United States.

The symptoms of PTSD manifest as the mind and body are processing the trauma, and they can be debilitating. Individuals with a prior history of depression and anxiety are at an increased risk of developing PTSD after a traumatic event, but it is important to note that PTSD can affect anybody, even if you have no prior history of a mental health disorder.

The manifestations of PTSD can vary, but it is generally described as repetitive, intrusive, re-experiencing of the trauma.

When a person with PTSD is triggered by an experience, stimuli, or memory, their fear response kicks in and results in symptoms such as:

  • Intrusive memories
  • Trigger avoidance
  • Mood problems
  • Sleep disruption
  • Anxiety
  • Disassociation
  • Memory problems

Although not everyone responds to trauma by developing PTSD, those who do often struggle to go about their daily lives.

Managing PTSD symptoms with CBD oil

One method that is gaining traction for relieving the symptoms of PTSD is cannabidiol (CBD) rich hemp oil. In addition to the many reports of improvement, there is a growing body of research that supports the use of CBD oil for this condition.

If you’re looking for a plant-based, holistic approach to managing the symptoms of PTSD, here’s what the research says about using hemp products.

What does the research say?

Cannabinoids are a series of compounds derived from the cannabis plant. These naturally-occurring compounds can be used for a variety of health conditions.

BD is one of over 100 cannabinoids found in hemp. It is commonly taken as a dietary supplement, but it is a popular choice for managing symptoms of PTSD and other conditions. However, it is not the only effective cannabinoid.

Cannabinol (CBN) is a compound that can aid insomnia, anxiety, and relaxation. It has strong sedative effects and is often used as a natural aid for sleep and de-stressing.

Cannabichromene (CBC) is another cannabinoid with amazing benefits. Research shows that CBC can be used to manage depression.

For PTSD, research shows that cannabinoids such as CBD, CBN, and CBC can help manage intrusive traumatic memories and promote significant improvements in the overall symptomatology of PTSD.

We are committed to bringing you the highest quality cannabinoid products

If you are considering using CBD-rich full spectrum hemp oils for PTSD symptoms, you should know that not all full spectrum hemp oils are the same.

Earth Science Tech has among the highest quality and purity of full spectrum industrial hemp oil naturally containing CBD on the market.

We don’t just focus on the cannabinoid CBD, in fact, we have a cannabinoid profile with a higher cannabinoid content compared to most other products on the market that call themselves full spectrum.

Our full spectrum hemp oil offers seven cannabinoids. Having all cannabinoids work together synergistically provides the most optimal benefits to our consumers.

Our products also go through a rigorous testing and research process. We have a third-party quality assurance testing process that ensures that we are delivering only the highest quality products.

We are also committed to researching the science behind CBD-rich full spectrum hemp oil. Many companies have only done clinical trial studies, but we have conducted clinical trials and university studies to ensure that we are always on the cutting edge of the CBD industry.

If you’re ready to see if Earth Science Tech’s CBD-rich full spectrum hemp oil products are right for you, visit our website to browse our offerings. If you’d like to discover more information about CDB or Earth Science Tech, visit our blog to learn more.

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What You Need to Know When Shopping for CBD Products

Answering these 5 questions can help you get great insight

Thanks in large part to the 2018 Farm Bill that was passed in December of last year, hemp has gotten a lot of attention. After years of being lumped together with marijuana, hemp is now no longer considered a drug, but a crop, and now it’s completely legal to grow and be used in various products.

Naturally, people are curious about the benefits it offers, especially when it comes to medical purposes. But because so many companies are now popping up with products containing cannabidiol (CBD) – the key compound found in hemp – it can be difficult figuring out what’s worth buying. Answering these questions can help.

1.  What do you want to use it for?

Because of the legal restrictions surrounding hemp, not a lot of research has been able to be conducted on it, so we probably won’t know for some time exactly what it can do. However, studies have shown that hemp oil could help with an assortment of ailments, including depression, anxiety, inflammation, epileptic seizures, and chronic pain. You should consider talking with your doctor about your specific condition and how hemp oil may be able to help.

2.  How do you want to take it?

Hemp oil now comes in a variety of forms. These include capsules, tinctures, powders, creams, and even gummies. How you take it may depend on what you’re taking it for. For anxiety or pain, for example, tinctures could be the most effective option, as this is a quick way for the body to absorb the cannabinoids.

3.  Isolate or full-spectrum?

Most hemp oil products will either come with an isolate or full-spectrum designation, and it’s important to understand what this means.

CBD isolate has been separated from all other cannabinoids in the hemp plant. The extraction method typically involves some sort of solvent, and then the CBD is filtered, heated, and made into a powder.

Superior full-spectrum hemp oil, on the other hand, utilizes a CO2 cold liquid extraction process to retain the therapeutic cannabis compounds that get stripped away in isolate form.

In addition to terpenes and flavonoids, this consists of many other cannabinoids. These include cannabidiol acid (CBDa), cannabidivarin (CBDV), cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC).

Each of these compounds has its own unique beneficial traits:

    • CBDV has been shown to be an effective anticonvulsant.
    • CBG can work to reduce inflammation.
    • CBDa is the acidic form of CBD
    • CBN has been found to have sedative properties.
  • CBD has antifungal properties.

It’s the combination of all of these compounds taken in the full-spectrum hemp oil that provides the best health benefits. When all the compounds work together, this is known as the entourage effect.

4.  Are there test results you can look at?

Any reputable company selling hemp products should provide consumers with test results or certificates of analysis (COAs), even if they’re not legally obligated to do so. They should be conducted by a third party and test not only the CBD but other cannabinoids and terpenes as well. Also, the results should reveal the presence of pesticides or any other contaminants. If you can’t find this information or it’s hard to obtain (or maybe it doesn’t exist), be wary.

5. What claims is the product or manufacturer making?

Another reason to stay away from a brand is if it is making unfounded health claims about its products. As mentioned, hemp oil has been shown to help people deal with different ailments, but results vary from person to person.

Only prescription drugs can come with labels saying that they treat certain ailments. If a hemp product makes this type of claim, not only is this misleading, the company will almost certainly run into trouble with the FDA.

Why Earth Science Tech produces the best CBD products on the market

If you’re going to use a hemp product, it’s important that it is made with the utmost quality ingredients, and our full-spectrum cannabinoid profile contains more cannabinoids at a higher content than other full-spectrum hemp oils on the market. This is what makes Earth Science Tech (ETST) superior.

We go to painstaking efforts to produce high-grade full-spectrum cannabinoid products that provide users with optimal benefits. We also use a third-party lab to test our products and all of its contents to ensure its purity. For any concerns or questions, please contact us. You can call 305-615-2118 or send us a message through our online form.

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What the 2018 Farm Bill Means for the Hemp Industry

As 2018 was ending, the hemp industry celebrated a big win

In December, Congress approved the 2018 Farm Bill, which changes the way hemp is treated in the U.S.—now, it will be seen as any normal crop instead of a “quasi-controlled substance.”

Here’s a look at what was approved in the bill and what it could mean for the cannabis industry.

Hemp farming and beyond

Hemp is one variety of cannabis that is considered non-psychoactive, meaning it doesn’t have the same brain-altering effects as marijuana. The 2018 Farm Bill legalizes hemp production, specifically of industrial hemp that has 0.3 percent or less of tetrahydrocannabinol (THC).

This is a big deal for the industry, in that it removes industrial hemp from the Controlled Substances Act of 1970, which sets forth regulations on illegal substances.

The 2018 Farm Bill will change the way farmers approach hemp agriculture. Two of the key changes to hemp production are:

  1. Industrial hemp is now legalized, including its extracts, cannabinoids and
  2. Hemp producers are now eligible for federal crop insurance.

States will now have a chance to regulate hemp production to take advantage of economic benefits. Also, federal grants from the U.S. Department of Agriculture will now be available to those who are researching hemp and its effects.

Government officials including Senate Majority Leader Mitch McConnell, an advocate of the bill, said back in June that much of the hemp products that American consumers are buying have been imported since American farmers weren’t able to farm hemp because of federal regulations related to cannabis.

The Farm Bill removes industrial hemp from those regulations, thus allowing American producers to get in on the profits.

What this means for CBD

Many in the cannabis extract market were happy to hear about the 2018 Farm Bill win for hemp, as hemp-derived cannabidiol (CBD) is now legal.

However, a day after the Farm Bill was signed by the president, the FDA released a statement with a clear message: they will still be rigorous about CBD inspections and regulations, and the legalization of industrial hemp doesn’t mean that producers can then put hemp into certain products and claim that they have health benefits.

The statement says that “This is because both CBD and THC are active ingredients in FDA-approved drugs and were the subject of substantial clinical investigations before they were marketed as foods or dietary supplements.”

As with any big change in regulations, the FDA wants to be sure that the market doesn’t go crazy with producers trying to take advantage of the potential benefits of the now-legal, hemp-derived CBD.

Predictions for the future

While some hemp farmers have already seen big impacts on their 2019 growing season, some are worried about the lack of testing standard details. One hemp producer’s director who talked to the Hemp Business Journal said that even though hemp crops have to be tested by certified labs, there are not really uniform testing standards yet, and states will have to decide how to approach the testing.

Another concern is that there will be too much hemp production since there isn’t a cap on how much can be cultivated per producer.

While the passage of the 2018 Farm Bill is a win for the hemp industry, it’s yet to be seen if this means a wider acceptance of cannabis, in general, can be expected. However, many states have been taking action, including Michigan, which voted to legalize recreational marijuana in 2018. The state now allows those over age 21 to carry up to 2.5 ounces of cannabis, though it’s still illegal to use on certain properties, like schools or other public properties.

Even though the future is still fairly unknown, predictions show that the industry is set to continue growing. By 2024, the cannabis industry is predicted to grow to $800 million in revenue.

The Hemp Business Journal predicts that the hemp industry will grow at a combined annual growth rate (CAGR) or 18.4 percent over the next five years and that by 2022 it will reach $1.3 billion.

The passage of the 2018 Farm Bill could be one step of many to come that move the cannabis and CBD industries forward.

Earth Science Tech (ETST) offers quality high-grade full-spectrum cannabinoid oil and is an innovative biotech company that operates in fields such as nutraceutical, pharmaceutical, medical device, research, and development. Contact us to learn more about our research or to learn more about our high-grade full-spectrum cannabinoids.

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Human Studies on Cannabidiol as a Treatment for Anxiety

Medical research shown shown that a chemical produced by the cannabis sativa plant reduces anxiety. This constituent of cannabis is called cannabidiol, or just CBD.

Cannabis has many constituents, but by far the most well known is tetrahydrocannabinol, or THC, the constituent which gets the user ‘high’. CBD however, has completely different effects from THC and is becoming more and more popular as multiple studies suggest that this substance is an anxiolytic, which means that it reduces anxiety and panic. CBD also diminushed the psychoactivity of THC, meaning that it can helps people that are using medical marrijuana to counter the unwanted “high” associate with THC present in that treatments.

CBD was discovered in 1940 by Dr. Roger Adams at the University of Illinois. At that time, cannabis was only known for its psychotropic constituent THC, so studies were mainly focused there. As a result, there was little done to explore and study the effects of CBD for many years. More recently, studies on CBD have been done first on animals and then on humans to determine exactly what CBD does in the body. Medicine has discovered that CBD does have many medicinal benefits, and we are starting to hear about them.

One of the pioneer study in 1993 compared CBD with Ipsapirone, diazepam and a placebo. Ipsapirone is an anxiolytic drug often used in research. Diazepam is a drug used to reduce anxiety in patients by working on chemicals in the brain that are unbalanced in people who suffer from anxiety. The study tested the different drugs and CBD on a set of healthy people. The subjects were subjected to a simulated public speaking test in order to create a stressful environment in which scientists could verify if CBD was anxiolytic. By measuring subjects’ heart ratea, blood pressure and skin conductance, the study showed that only Ipsapirone decreased anxiety during public speaking, CBD decreased anxiety that occurred after the test, and diazepam was effective before and after the test, but not during the test. The study suggested that CBD and Ipsapirone had anxiolytic properties.

A more recent study in 2004 investigated the effects of CBD on regional cerebral blood flow by doing single-photon emission computed tomography (SPECT) scans on the subjects. This scan gives doctors three pieces of information: areas of the brain that work well, areas of the brain that are low in activity, and areas that are high in activity. Doctors can then determine if the subject needs specific medicine to regulate certain areas that need to be balanced. Since in this case study, the test itself was stressful, it was a good way to test CBD. The results showed that CBD reduced anxiety, according to blood flow, and was compatible with regular blood flow.

In more than one study, it was also discovered that the effects of dosage levels act in a U-shaped curve. Small dosages of 100mg of CBD were ineffective, dosages of 300mg to 600mg were most effective and treatments over 900mg of CBD were also ineffective.

In 2009, another study made the use of functional magnetic resonance imaging (FMRI), which produces more images with higher resolution and gives a clearer image of the levels of activity in the brain, to see if CBD had anxiolytic effects. They tested 15 healthy people and the results showed that CBD did reduce the anxiety caused by the stress of the FMRI.

A Brazilian study done in 2010 found that Cannabidiol has therapeutic potential with antipsychotic, anxiolytic, and antidepressant properties, in addition to being effective in treating other conditions on subjects with psychiatric disorders and in healthy subjects. These findings suggest that CBD may be effective is treating patients with anxiety as a mental illness.

 

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Hygee™ is almost here!

All of us at Earth Science Tech are really excited following the announcement that  Hygee, our first medical device product, is going to have its first commercial production run. We’re only making 5,000 Hygee to start because it’s a full-production test of our manufacturing system, but we’re all pretty confident that things will go fine. We expect to launch Hygee in March, in Vietnam first. It takes a lot of time and paperwork to get a medical device certified in the US and Canada, so our first markets will be in Asia and South America.

What is Hygee?
In case you don’t know, Hygee is a new kind of tool to help women find out if they are infected with Chlamydia, a very serious Sexually Transmitted Infection, or STI, that can have very bad effects on infected women and their babies. The thing is, Chlamydia is easy to cure with antibiotics. What’s hard is getting women tested so they know that they have it. That’s what Hygee does. Hygee makes it very simple for a woman to get tested for Chlamydia (and Gonorrhea soon); quietly, privately, without even the family doctor knowing. If she is infected, she will have to tell a doctor to get treated, but not until then.

Why

Basically, Hygee looks like a very thin menstrual pad, just like the pads that millions of women wear when they have their period; but it’s not a menstrual pad and it can’t be used during menstruation. The kit will be available online or in pharmacies. When a woman wears the Hygee pad for at least four hours (you can wear it all day if you want) the pad collects a cervical cell sample and holds it safely in suspension. Then, she puts the pad in the envelope that comes in the kit, tears the information tab off the envelope, and drops it in the mail. It goes directly to our lab where the actual testing is done. A few days later, all she has to do is either go online or phone the lab. There’s a number on the information tab that she will need to get her results. That’s it. No visit to the doctor, no vaginal swab, no clinic, nobody knows.

Why is all this so important?

It’s important because not only is the disease easily transmitted to sexual partners through unprotected sex, women who are infected and don’t get treatment can have serious heath complications, up to and including sterility! Plus, if a woman is pregnant, Chlamydia is major cause of infants being born blind, or stillborn. We’re not kidding here, this is a serious disease that affects women more than men.

The World Health Organization recommends that all sexually active women aged 15 to 25 years old get tested yearly for Chlamydia. There are more than 130 million new Chlamydia cases yearly, and Hygee is dedicated to helping control the silent Chlamydia epidemic. (We’re going after Gonorrhoea next, but that’s not ready yet.)

So yes, we’re really excited to see the first batch roll off the production line. The whole team believed in the success of Hygee from Day One, and we all feel that we’re not just a business selling a product, we’re doing everything we can to protect women and their future babies from the terrible, adverse effects of chlamydia and other STIs.”