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CEO & Collaborators Gonorrhea Medical Sexually Transmitted Infections

Why Hygee is important now: The Medical Case

We can start with a basic reality. The incidence of Sexually Transmitted Infections (STI) has reached epidemic proportions. This epidemic has serious implications for people and for our society, and they fall into two categories: health and economic. In this blog post, I’m going to talk about the effects on health, and I’ll talk about money and business next post.

There are a lot of STI. Some STI are viral, some caused by parasites, and some are bacterial. Bacterial infections are the most easily treatable because we have antibiotics for them. There are four major bacterial STI: chlamydia, gonorrhea, syphilis, and trichomoniasis. In the United States alone, the Centres for Disease Control reported this past August* that between 2013 and 2017 the number of people infected has increased greatly.

  • Chlamydia is the most common STI More than 1.7 million cases were diagnosed in 2017, 45% in 15- to 24-year-old women.
  • Gonorrhoea diagnoses increased 67% overall to 555,608 new infections in 2017, and nearly doubled among men (from 169,130 to 322,169). Infections in women increased in 2017 for the third year in a row.
  • Syphilis diagnoses increased 76%, although overall the numbers for this infection are much smaller than the other two.
  • The CDC did not report figures for trichomoniasis, but we can easily assume that the number of infections is growing rapidly as well,

Worldwide, the numbers are alarming, yet I have to point out, that the Americas, which include, Canada and the United States, two countries that invest a huge amount of money in modern healthcare systems, show higher rates of chlamydia and trichomoniasis than any other region.

As I said, all of these are curable with antibiotics, yet most cases aren’t diagnosed and aren’t treated. Untreated chlamydia can have severe effects on women and on the babies of untreated women. These include infertility, ectopic pregnancies, babies born blind or stillborn, and increased HIV risk.

New research suggests that one or two strains of chlamydia can also morph into trachoma, a tropical disease, which can cause blindness in the woman herself.

Why is this happening? Why do STI go undiagnosed and untreated, even in First World countries? There is a stigma around STI. People who are infected are shamed, and looked down on. Especially young woman who may be afraid to access medical help because their parents might be informed. In the US, healthcare is still subject to socioeconomic factors like poverty and access to clinics.

Hygee is important because it gives women the tool they need to get diagnosed on their own. A girl or woman will be able to buy the kit from a pharmacy or order it online. All she has to do is wear the pad for a minimum of four hours, put the pad in the envelope, tear off the envelope’s tab, and put it in the mail. The ETST partner lab will do the testing. She never puts her name on the test; there is just a number on the pad, the envelope, and the tab she keeps. A few days later, she can go online or phone the lab toll-free. She uses the number on the tab to access her results. If she is not infected, then no one will ever know she even decided to get tested.

If she is infected, the lab or the website will tell her what to do. She will have to see a doctor to get the antibiotics she needs to talk to kill the infection. She will have to be sure not to have unprotected sex until she has finished her course of antibiotics, and hardest of all, she should inform her partner(s) that she was infected that they have to get tested and treated as well. That is not so private, but it’s the only way to stop the spread of the disease.

Hygee will make it easy and private for women to get tested, and improved access to testing is the first step in stemming this massive, destructive epidemic.

The costs of STI infections aren’t just human health they are also economic. Next time.

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Cannabinoids Cannabis Oils Cannabis Plant CEO & Collaborators Hemp Oil Industrial Hemp Medical

Human Studies on Cannabidiol as a Treatment for Anxiety

Medical research shown shown that a chemical produced by the cannabis sativa plant reduces anxiety. This constituent of cannabis is called cannabidiol, or just CBD.

Cannabis has many constituents, but by far the most well known is tetrahydrocannabinol, or THC, the constituent which gets the user ‘high’. CBD however, has completely different effects from THC and is becoming more and more popular as multiple studies suggest that this substance is an anxiolytic, which means that it reduces anxiety and panic. CBD also diminushed the psychoactivity of THC, meaning that it can helps people that are using medical marrijuana to counter the unwanted “high” associate with THC present in that treatments.

CBD was discovered in 1940 by Dr. Roger Adams at the University of Illinois. At that time, cannabis was only known for its psychotropic constituent THC, so studies were mainly focused there. As a result, there was little done to explore and study the effects of CBD for many years. More recently, studies on CBD have been done first on animals and then on humans to determine exactly what CBD does in the body. Medicine has discovered that CBD does have many medicinal benefits, and we are starting to hear about them.

One of the pioneer study in 1993 compared CBD with Ipsapirone, diazepam and a placebo. Ipsapirone is an anxiolytic drug often used in research. Diazepam is a drug used to reduce anxiety in patients by working on chemicals in the brain that are unbalanced in people who suffer from anxiety. The study tested the different drugs and CBD on a set of healthy people. The subjects were subjected to a simulated public speaking test in order to create a stressful environment in which scientists could verify if CBD was anxiolytic. By measuring subjects’ heart ratea, blood pressure and skin conductance, the study showed that only Ipsapirone decreased anxiety during public speaking, CBD decreased anxiety that occurred after the test, and diazepam was effective before and after the test, but not during the test. The study suggested that CBD and Ipsapirone had anxiolytic properties.

A more recent study in 2004 investigated the effects of CBD on regional cerebral blood flow by doing single-photon emission computed tomography (SPECT) scans on the subjects. This scan gives doctors three pieces of information: areas of the brain that work well, areas of the brain that are low in activity, and areas that are high in activity. Doctors can then determine if the subject needs specific medicine to regulate certain areas that need to be balanced. Since in this case study, the test itself was stressful, it was a good way to test CBD. The results showed that CBD reduced anxiety, according to blood flow, and was compatible with regular blood flow.

In more than one study, it was also discovered that the effects of dosage levels act in a U-shaped curve. Small dosages of 100mg of CBD were ineffective, dosages of 300mg to 600mg were most effective and treatments over 900mg of CBD were also ineffective.

In 2009, another study made the use of functional magnetic resonance imaging (FMRI), which produces more images with higher resolution and gives a clearer image of the levels of activity in the brain, to see if CBD had anxiolytic effects. They tested 15 healthy people and the results showed that CBD did reduce the anxiety caused by the stress of the FMRI.

A Brazilian study done in 2010 found that Cannabidiol has therapeutic potential with antipsychotic, anxiolytic, and antidepressant properties, in addition to being effective in treating other conditions on subjects with psychiatric disorders and in healthy subjects. These findings suggest that CBD may be effective is treating patients with anxiety as a mental illness.

 

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CEO & Collaborators Gonorrhea Sexually Transmitted Infections Top Stories

Hygee™ is almost here!

All of us at Earth Science Tech are really excited following the announcement that  Hygee, our first medical device product, is going to have its first commercial production run. We’re only making 5,000 Hygee to start because it’s a full-production test of our manufacturing system, but we’re all pretty confident that things will go fine. We expect to launch Hygee in March, in Vietnam first. It takes a lot of time and paperwork to get a medical device certified in the US and Canada, so our first markets will be in Asia and South America.

What is Hygee?
In case you don’t know, Hygee is a new kind of tool to help women find out if they are infected with Chlamydia, a very serious Sexually Transmitted Infection, or STI, that can have very bad effects on infected women and their babies. The thing is, Chlamydia is easy to cure with antibiotics. What’s hard is getting women tested so they know that they have it. That’s what Hygee does. Hygee makes it very simple for a woman to get tested for Chlamydia (and Gonorrhea soon); quietly, privately, without even the family doctor knowing. If she is infected, she will have to tell a doctor to get treated, but not until then.

Why

Basically, Hygee looks like a very thin menstrual pad, just like the pads that millions of women wear when they have their period; but it’s not a menstrual pad and it can’t be used during menstruation. The kit will be available online or in pharmacies. When a woman wears the Hygee pad for at least four hours (you can wear it all day if you want) the pad collects a cervical cell sample and holds it safely in suspension. Then, she puts the pad in the envelope that comes in the kit, tears the information tab off the envelope, and drops it in the mail. It goes directly to our lab where the actual testing is done. A few days later, all she has to do is either go online or phone the lab. There’s a number on the information tab that she will need to get her results. That’s it. No visit to the doctor, no vaginal swab, no clinic, nobody knows.

Why is all this so important?

It’s important because not only is the disease easily transmitted to sexual partners through unprotected sex, women who are infected and don’t get treatment can have serious heath complications, up to and including sterility! Plus, if a woman is pregnant, Chlamydia is major cause of infants being born blind, or stillborn. We’re not kidding here, this is a serious disease that affects women more than men.

The World Health Organization recommends that all sexually active women aged 15 to 25 years old get tested yearly for Chlamydia. There are more than 130 million new Chlamydia cases yearly, and Hygee is dedicated to helping control the silent Chlamydia epidemic. (We’re going after Gonorrhoea next, but that’s not ready yet.)

So yes, we’re really excited to see the first batch roll off the production line. The whole team believed in the success of Hygee from Day One, and we all feel that we’re not just a business selling a product, we’re doing everything we can to protect women and their future babies from the terrible, adverse effects of chlamydia and other STIs.”